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Tuesday, August 12, 2008

Research Associate II

Human Genome Sciences
Rockville, MD


Human Genome Sciences (HGS) is located in the Washington, DC metro area, and was founded in 1992 with the goal of creating a global biopharmaceutical company to discover, develop, manufacture, and market gene-based drugs to address unmet medical needs. We have a significant product pipeline with seven products in clinical development, including drugs to treat hepatitis C, lupus and other autoimmune diseases, anthrax exposure, and cancer. In recent years, we have progressed toward becoming a late stage development and commercialization company, and we have recently started Phase 3 trials for three of our key development programs.

HGS is developing an innovative new treatment for systemic lupus erythematosus (SLE), which would be the first new treatment for lupus in nearly 40 years. This product, belimumab, is being co-developed and commercialized with Glaxo SmithKline. We are also developing a long-acting interferon alpha, Albuferon, for Hepatitis C, along with Novartis. HGS has also been awarded a two-phase contract with US government to supply them with ABthrax, a monoclonal antibody treatment for anthrax, for the Strategic National Stockpile, which we expect to deliver in 2008.

At HGS, people are the key to our success. We share a passion for scientific and business innovation, creating unique opportunities to contribute to the commercialization phase of our products. At HGS, you will have opportunities to learn and grow, interacting with talent of the highest caliber, and you will be supported by a culture committed to employee and leadership development. We offer a competitive salary and benefits package. HGS is an Equal Opportunity Employer EOE/AA M/F/D/V

Please visit www.hgsi.com for further information on our company and to apply on-line for this position.

Human Genome Sciences (HGS) is an innovative organization which emerged at the forefront of the genomics revolution in 1992. The organizational goal is to discover, develop, manufacture, and market products which focus on addressing largely unmet medical needs or areas where significant improvement can be made to existing medical regimens. We are located in the Washington DC metropolitan area.

When the company was first established, HGS primarily focused its efforts in discovery research. HGS has progressed in recent years towards becoming a fully integrated company, having built a strong drug development and manufacturing organization. HGS currently has over 860 employees and boasts a strong pipeline with five products in clinical development, including drugs to treat Hepatitis C, lupus and other autoimmune diseases, anthrax exposure, and cancer. Three of these are at an advanced stage and are currently undergoing Phase III trials. HGS expects both of these products to be launched in 2010. HGS is also initiating additional pre-clinical work in the immunology and oncology areas to develop new products to add to their early stage pipeline.

This is an excellent opportunity for a highly motivated Research Associate to become part of a group recently established to develop and validate biomarkers in support of non-clinical research and clinical trials. The individual will implement and confirm biomarker assays for oncology and immunology projects. Strong experience in molecular and cellular biology is a must; specifically, PCR technologies, RNA/DNA isolation, microarray platforms, and cell culture. Additional experience in protein and DNA electrophoresis, immunoblot analysis, and flow cytometry is a plus. Knowledge and experience in assay development and database maintenance would be beneficial.

At HGS, you will have opportunities to learn and grow, interacting with talent of the highest caliber, and you will be supported by a culture committed to employee and leadership development

Requirements: The ideal candidate will have a bachelors or masters degree in oncology, immunology, cell biology, or a related field, with at least one to two years of relevant lab experience. The successful candidate should have a good understanding of oncology and immunology and practical knowledge of biological, immunochemical, or biochemical methodologies. The individual should be creative and have a record of biomarker discovery and validation. The ability to independently troubleshoot experiments and author technical reports with minimal supervision is essential. Excellent documentation and communication skills are expected.

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