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Sunday, July 27, 2008

Laboratory Coordinator / Research Associate

Georgetown University, Department of Human Science
Washington, DC


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Description: Incumbent will be responsible for Laboratory safety, preparation and maintenance of all lab materials required for laboratory courses taught within the Department of Human Science. Currently this is up to eight laboratory sections each semester that accommodate approximately 200 students. Instructional activity may include providing additional materials on an as needed basis and answering last minute questions that may arise; Timing of the preparation of materials for all students simultaneously; running experiments to ensure reagents and supplies will work; setting up labs on the day of the experiments in a clear and concise manner. Lab preparation and experiment implementation also includes significant coordination and instruction of students. There may also be prep sessions for faculty and other instructors to provide details on materials and supplies that will be available in the labs, step-by-step procedures on what students are supposed to do and the results that are expected, demonstrations and explanations of tests and responses to technical questions that may be asked and arranging for one-on-one demonstrations after lab sessions or launching meetings. Responsible for all lab safety, including but not limited to checking the eyewash stations, making sure fire extinguishers have been inspected, and that safety signs are visibly displayed. Coordinate logistics for lab related meetings including reserving conference room and if appropriate, provide light refreshments. Order and maintain adequate inventory of supplied, equipment, reagents, and stock solutions for all laboratory components of Human Science courses. Ensure purchases are made within budget guidelines. Obtain best prices by comparative shopping within various scientific vendors. Obtain prior approval from the course supervisor/instructor/director of record for any exceptions. Maintain all purchasing records for the teaching and the research laboratories, prepare monthly summary for auditors and perform weekly radiation safety surveillance and maintenance records. Manage technical aspects of assigned projects and develop lab protocols and procedures. Prepare the reagents for the day of the experiment, grade tests and submit results to the course directors. Must ensure compliance with all environmental health and safety (EHS) regulations including collection, autoclaving and disposal of biohazard waste from lab preparations and from student experiments. Perform research studies using techniques of molecular biology such as electrophoresis, polymerase chain reaction, preparation and analysis of DNA & RNA, and isolation and purification of proteins, immunohistochemistry and Western blotting. Responsible for tissue culture based assays as a main research activity. Present relevant data at weekly meetings to PIs, Directors, Co-workers and other research staff. Gather and analyze data, formulate conclusions, prepare and write reports for submission to scientific journals.

Practical Experience: Bachelor’s degree with at least three – five years performing various biology and microbiology procedures. Ability to read fungal and bacterial cultures preferred. Knowledge of research laboratory skills – including preparation of stock solutions, research using molecular biology techniques including DNA & RNA isolation and purification of protein. Excellent math skills required; tissue culture skills; experience in molecular biology preferred. Knowledge of necessary supplies and materials for hands-on laboratory for undergraduate Nursing and Health Studies students. Must have excellent communication skills with ability to prioritize, exercise independent judgment and make decisions without conformation from supervisor before action.

Postdoctoral Position in (NCI)

Apoptosis Deregulation & Targeting in Cancer
Dr. King Kwong
NCI, Bethesda, MD


Description: We are looking for a highly motivated individual to join our laboratory team in developing novel treatments which target the apoptosis pathways in cancer. Our laboratory has a focus on chest malignancies such as lung cancer, esophageal cancer, and pleural mesothelioma.

Applicants should possess a Ph.D., M.D., or equivalent degree. The position involves the ability to discuss scientific data and strategy with diverse members of the team and with collaborators, so fluency in the English language is required. Candidates must have an excellent understanding of cancer biology, molecular biology techniques, and small animal models. A detailed knowledge of how to design and perform scientific work independently and collaboratively is a must. Prior experience in molecular laboratory-based cancer research or previous work in the field of apoptosis is desirable. The successful candidate may need to complete an on-site interview process and deliver a brief research presentation.

Location: NCI -- Clinical Research Center -- Bethesda.

The appointment duration is up to 5 years. Stipends are commensurate with education and experience.

Please click on the button below, or send an application letter, an up-to-date CV, names and contact information for 3 letters of reference, and a list of publications to:

King F. Kwong, M.D.
Principal Investigator
National Cancer Institute
CRC Room 3-3940
Bethesda, MD 20892

Phone: (301) 435-7504
Fax: (301) 451-6934
E-mail: kwongk2@mail.nih.gov

This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs.

Senior Manager, Pharmaceutical/Medical Device Quality Management

Otsuka America Pharmaceutical, Inc.
Rockville, MD

Description: Otsuka America Pharmaceutical, Inc. (OAPI) is a successful, innovative, fast-growing healthcare company that commercializes Otsuka-discovered and other product opportunities in North America, with a strong focus on and commitment to neuroscience, cardiovascular and gastrointestinal therapeutic treatments.

Otsuka is seeking a Senior Manager, Pharmaceutical/Medical Device Quality Management with the ability to employ a variety of quality methodologies required to support international technical and regulatory requirements. This person will have the opportunity to work with a highly skilled work force from around the world and support them in understanding US regulations and requirements.

The specific duties assigned to the Senior Manager, Pharmaceutical/Medical Device Quality Management are as follows:
  • Responsible for product release - commercial, device and investigational materials.
  • Responsible for the maintenance of the Quality System.
  • Interfaces with project teams to assure that the goals set by the team are consistent with relevant governmental requirements, including but not limited to the US.
  • Maintains and oversees the development of departmental Standard Operating Procedures, Quality System Regulation (QSR) manual, etc.
  • Responsible for assuring that our partners and OAPI meet their contractually agreed to quality commitments. Contract development will be a task that arises from time to time.
  • Participates in the selection of suitable third party contractors, including but not limited to Auditing potential and current suppliers to assure compliance with cGMP and other relevant regulations.
  • Works in cooperation with all OAPI and OPDC, as well as other CROs, to facilitate processing of materials to the clinic and adhere to timelines.
Requirements . The successful candidate must meet the following minimum requirements:
  • BS in Chemistry, Chemical Engineering or Physical Sciences
  • 7-10 years experience in Pharmaceutical and/or Device manufacturing environment in the quality areas
  • Experience in supervising a small staff and mentoring existing personnel
  • Proficient in managing professional individuals in a matrix environment
  • Fully understands and comprehends the cGMP, including Part 11 and regulations pertaining to medical devices, Parts 812 and 814, etc.
  • Willing to work with a dynamic group that takes a multi-disciplined team approach to executing and achieving departmental and corporate goals
  • Willing to travel domestically and internationally approximately 25% of their work schedule.

We offer a competitive compensation and benefits package plus a positive work environment, which encourages personal growth and achievement.

For immediate consideration, qualified candidates should apply online at www.otsuka.com. Click on OAPI, Careers, then Employment Opportunities. Enter 07-035 for keyword search. Due to the volume of resumes, only applicants considered for interviews will be contacted.

Otsuka is an Equal Opportunity Employer.

Research Associate II (Gene Logic)

Gene Logic
Gaithersburg, MD



DESCRIPTION: Gene Logic is looking for a Research Associate II.

Proficient at the duties of a Research Associate II:
  • Analyzes routine data and interprets scientific and Quality Control results accurately.
  • Mastered theoretical knowledge of molecular biology and other scientific disciplines and applies this knowledge to improving and troubleshooting production processes.
  • Able to conduct experiments with limited guidance.
  • Able to make recommendations to changes in protocols.
  • Initiates changes in Standard Operating Procedure for modifications of existing processes.
  • Ability to operate more advanced laboratory equipment and provide detailed maintenance.
  • May write standard operating procedures and protocols. Other duties as assigned.

REQUIREMENTS
  • B.S. in a Scientific Discipline with 3 or more years of experience preferred
  • PCR and/or nucleic acid extraction experience a plus.

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