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Monday, July 28, 2008

Staff Scientist (NCI)

Carcinogen-DNA Interactions Section
LCBG, NCI, Bldg 37 NIH
Bethesda, MD, 20892-4255

The CDI Section investigates the extent, persistence, and biological consequences of DNA damage, with the intention of applying the knowledge gained to elucidate mechanisms of toxicology, cancer causation and cancer prevention in humans. The current Staff Scientist position is for the study of antiretroviral nucleoside reverse transcriptase inhibitors (NRTIs) given to human immunodeficiency virus-infected individuals, including pregnant women. CDI studies have revealed DNA damage, mutagenesis and cancer induction in mouse offspring exposed transplacentally to the NRTI zidovudine (AZT), as well as mitochondrial compromise and nuclear DNA damage in mouse, monkey and human offspring exposed in utero to NRTIs.

The Staff Scientist position is for a PhD, with expertise/training in biochemistry, toxicology, pharmacology or chemical carcinogenesis, to lead a team effort focused on NRTI-induced mitochondrial DNA damage and mitochondrial toxicity. The CDI Section employs a breeding colony of Erythrocebus patas monkeys, maintained at a local contract laboratory and given human-equivalent NRTI combinations. As the liaison person for this work the candidate Staff Scientist will design human-equivalent protocols and perform biomarker studies to evaluate infant nuclear and mitochondrial integrity. The candidate will also help identify agents designed to attenuate NRTI-induced toxicity, and thereby protect exposed children from cardiac muscle loss that can appear in childhood. The candidate will perform biomarker studies with human infant tissues, as correlations between human and monkey provide powerful insights into mechanisms underlying human NRTI-induced toxicities.

The candidate will exercise a high degree of independence in these investigations within the framework of the scientific question of interest. In addition to performing/managing the current biomarkers, the candidate will be encouraged to design biochemical and molecular approaches to relevant questions. The successful candidate must have an M.D. or Ph.D. degree, and should submit:

• a current curriculum vitae, complete bibliography
• a statement of research interests
• names and contact information for four professional references

Applications should be sent – preferably by EMAIL – to:

Dr. Miriam C. Poirier, Head CDI Section, LCBG, NCI
Bldg 37, Rm 4032, NIH
37 Convent Dr, MSC-4255
Bethesda, MD 20892-4255
Phone: 301-402-1835
EMAIL: poirierm@exchange.nih.gov

HHS and NIH are equal opportunity employers.

Postdoctoral Position (NIH)

Innate Immunity and Liver Disease with Dr. Bin Gao

Department of Health and Human Services
National Institutes of Health

A postdoctoral fellow position is available to study the role of innate immunity in liver diseases. Candidates motivated to study liver immunology and with experience in flow cytometry, small animal surgery, molecular biology, and cell biology are encouraged to apply. Skills in oral and written communications are essential. Candidate must have a Ph.D. or M.D. degree and have less than five years of postdoctoral experience. Compensation will be commensurate with relevant work experience.

Interested candidates should click on the button below, or submit a C.V., list of publications, and three letters of reference to: Dr. Bin Gao, Section on Liver Biology, Laboratory of Physiologic Studies, NIAAA, NIH, 5625 Fishers Lane, Room 2S-33, Bethesda, MD 20892-9413, or e-mail bgao@mail.nih.gov.

Women, minorities, and persons with disabilities are strongly encouraged to apply.

The NIH is dedicated to building a diverse community in its training and employment programs.

Research Scientist (Developmental Biology)

Manassas, VA


Founded in 1925, ATCC has a well-earned reputation as a premier biological resource center. Our professional staff is dedicated to providing products, services and standards that support global health and translational research in such critical areas as malaria, infectious diseases and vaccine production.

Requirements: PhD in molecular biology, biochemistry or related discipline required. A minimum of 3 years industrial (pharmaceutical, biotechnology) experience in stem cell research required. Must have hands-on experience with gene expression profiling, molecular cloning, quantitative RT-PCR, microarray data analysis, Western blotting, ELISA and cell culture. Good publication record in peer-reviewed journals and proposal writing skills preferred. Experience with team-based collaborations a must.

We are proud to be an EEO/AA employer M/F/D/V.

Click here for additional opportunities at ATCC.

Genetics Counselor

Baltimore, MD


Job Description : Interprets results of genetic tests to physicians and genetic counselors and assist them in determining others at risk for a specific genetic disorder.
  • identification of families at risk,
  • collection of family, pregnancy and medical history information,
  • assessment and interpretation of information which places family at risk,
  • patient education and review of options through counseling,
  • coordination of testing with laboratories,
  • providing results to patient and physician,
  • provision of ongoing supportive counseling,
  • acting as a patient advocate,
  • referring families to various support services,
  • dictation of clinical summary letter,
  • collecting follow-up information.
1. Counseling to occur either in-person, or telephone, or web-based.
2. Provide pregnancy risk counseling which consists of:
  • assessment of risks associated with teratogenic exposures (i.e., occupational, chemical, medication, drug, illness),
  • identification and scheduling of patients with increased risks,
  • providing telephone counseling regarding lower risk exposures,
  • answer medical professionals' inquiries about exposures.
  • assessment of risks associated with multiple fetal gestations and fetal reductions
  • review any risks associated with infertility treatments, such as ICSI
  • review risks associated with monoamniotic multifetal pregnancies
  • review risks associated with fetal reduction
1. Provide preconceptional counseling for couples contemplating pregnancy
2. Provide cancer risk assessment counseling for individuals with a personal or family history of cancer.
3. Educate and train local sales teams and other LabCorp employees on genetic issues as well as the genetic issues association with genetic testing offered by LabCorp
4. Participate in the continuing education of genetic counseling and LabCorp genetic counselors
5. Assist in providing regional genetic education programs for physicians, nurse and other medical staff
6. Educate genetic counseling students, residents, medical students, MFM and Genetic fellows, physicians, and other medical professionals about genetics, prenatal testing, preconception and cancer risk assessment services.

Other Responsibilities : This position may require the genetic counselor to travel throughout the metro Baltimore area to provide genetic counseling services to other LabCorp clients. The counseling will be provided either in the client’s office or a LabCorp PSC.
The Genetic Counselor would be required to work with the SMEs, KAEs, and HBG to promote the Genetic Counseling Service to the local physicians in order to grow the referral base.

Job Requirements : Master's Degree in Genetic Counseling w/2 years of experience.

Undergraduate Internship (DC)

The National Academies
Corporate Headquarters - DC
Div on Engineering & Physical Sciences


Basic Requirements: High School diploma, GED, or equivalent knowledge. Current enrollment in an undergraduate degree college or university program.

The SSB Lloyd V. Berkner Space Policy internship program is aimed at undergraduate students majoring in physics, astronomy, chemistry, biology, or geology. Undergraduates at all stages of their studies are encouraged to apply, but those who have completed their junior year are desired.

Description: The Space Studies Board (SSB) provides an independent, authoritative forum for information and advice on all aspects of space science and applications. It oversees advisory studies and program assessments, facilitates international research coordination, and promotes communications on space science and science policy between the research community, the federal government, and the interested public.

The Intern will perform a number of basic research functions and activities that facilitate the research efforts of staff researchers. Conducts searches and compiles information or data and may assist in analyzing basic research results. Tasks may include data entry and extraction, data conversion, manipulation, retrieval, editing, documentation, and formatting charts, graphic displays and tables. May assist with administrative duties related to programs/projects.

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