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Tuesday, July 29, 2008

Postdoctoral Position

Postdoctoral position is available for highly motivated, energetic individual with interests in studying the underlying systems leading to tumorigenesis with the goal of the development of novel therapies based on an understanding of the tumor cell biology. The model system we study in the pediatric tumor, Neuroblastoma. Individuals with a background in developmental biology/ stem cells, epigenetic regulation or signal transduction are encouraged to apply. Our laboratory's research is currently focused on: mechanisms of differentiation in pediatric tumors and transcriptional control of differentiation in normal model systems and tumor cells. Approaches include molecular biology, genomics, biochemistry, cell biology and animal modeling.

Carol J. Thiele PhD
email: ct47a@nih.gov
Visit our website for more information. http://ccr.cancer.gov/staff/staff.asp?profileid=5597

Note: Applicants must have a Ph.D. and/or M.D. Less than five years of postdoctoral experience is preferred. This position is subject to a background investigation.

Postdoctoral Fellow (Drug Development)

CLICK HERE TO APPLY


ImQuest BioSciences is a leading Contract Research Organization specializing in the preclinical development of anti-cancer and anti-infective drugs, microbicides, and vaccines. We presently have an opportunity for a Postdoctoral Fellow with experience in infectious disease drug and topical microbicide development with expertise in microbiology, molecular virology, cell biology, and/or drug development to participate in programs to discover and develop novel therapeutic and preventative agents.

The Postdoctoral Fellow will be responsible for the following activities:

The successful candidate will possess a Ph.D. with experience in microbiology or related field with a desire to establish a professional reputation of excellence in drug and topical microbicide development. ImQuest provides a highly scientific and challenging research environment focused on applied pharmaceutical research, utilizing novel and cutting edge technologies to support the development of products for use in the treatment of human infectious disease and cancer. Our world-reknowned programs in HIV drug and topical microbicide research provide fertile ground for training programs for innovative and focused scientists interested in developing products for treating human disease. Our microbiology programs are broad based and include HIV, hepatitis, influenza, herpes, and sexually-transmitted disease research with expertise in virology, bacteriology, immunology, cell biology, molecular biology, assay development, and drug development technologies.

Specifically, the Postdoctoral Fellow will be responsible for laboratory research involved with the development of HIV therapeutic and microbicide products and the submission of grant proposals to obtain support for the development activities. Additionally, associated projects will include interaction with other scientists and projects involved in our infectious disease research programs. The candidate should have experience with the use of Microsoft Office products (Word, Excel, Powerpoint), possess excellent verbal and written communication skills, and demonstrated ability to be proactive, work independently but as a member of interactive research teams, and be an effective multi-tasker.

ImQuest offers a highly competitive compensation package which includes company stock options, health and dental insurance, educational benefits and 401K plan.


Postdoctoral Position

Mechanisms of Cellular Signaling, Dr. Mihaela Serpe
NICHD, NIH
Bethesda, MD

Click here to apply

Postdoctoral positions are available in the Unit on Cellular Communication, Program in Cellular Regulation and Metabolism, in the National Institute of Child Health and Human Development.

Our unit studies molecular mechanisms of cellular communication during development using the Drosophila melanogaster model system. We use a variety of biochemistry, molecular biology, and genetics approaches to study genes that modulate the function of TGF-beta superfamily of growth and differentiation factors. We are interested in how the extracellular availability of TGF-beta factors is regulated in time and space and what is the role of the cell surface in local activation of TGF-beta-type signaling. Future projects focus on 1) the role of BMP regulatory proteins in the nervous system development and homeostasis, and 2) characterization of tethering mechanisms that appear to spatially restrict signaling.

Additional information about our research may be found at http://ucc.nichd.nih.gov/.

Applicants must have a Ph.D. degree and less than five years of postdoctoral experience. A strong background in molecular biology, biochemistry, cell biology, or developmental biology is required. Experience with the fruit fly model system is desirable.

Research Assistant

American Red Cross
Gaithersburg, MD

REFERENCE CODE: 7160BR

CLICK HERE TO APPLY

About the Red Cross
The American Red Cross touches millions of lives each year. American Red Cross employees and volunteers help keep the public prepared to respond to disasters and personal emergencies. The Red Cross provides training in lifesaving skills such as CPR and first aid, collects and distributes half the nation's blood supply, and helps victims of more than 67,000 disasters annually. If you are looking for a fast paced, challenging position in a nonprofit setting.....just consider the opportunities!

Our humanitarian mission connects us to people and communities across the nation and around the world. We are committed to ensuring that our people, programs and services reflect the diversity of the people and communities we serve. We encourage you to join us on this journey and experience the greatness of the human spirit at its best.

About the Research Assistant Position
Performs research in collaboration with others for upcoming study. Makes detailed observations, analyzes data and interprets results. Prepares technical reports, summaries, protocols, and quantitative analyses. Maintains familiarity with current scientific literature. Contributes to project process within his/her scientific discipline. Investigates, creates and develops new methods and technologies for project advancement. Maintains high level of professional expertise through familiarity with scientific literature. May participate in scientific conferences and contribute to scientific journals. May be responsible for identifying patentable inventions. Uses professional concepts in accordance with company objectives to solve complex problems in creative and effective ways.

RESPONSIBILITIES:
Conducts research or development activities following prescribed protocols or procedures. Documents procedures followed, notes results, discrepancies or deviations, and accumulates data/results according to project methodology. Organize or aggregates results into form in which they can be readily interpreted by scientific/project staff. May participate in intellectual property evaluations and development of patent applications.

QUALIFICATIONS:
Four year degree in Biology, Chemistry, Medical Technology or relevant field or equivalent combination of training and experience; plus a minimum of three years related experience is required. Demonstrated working knowledge of scientific principles and research procedures. Knowledge of cGLP and accepted procedures for working with hazardous biological substances.

The American Red Cross National Headquarters is an Equal Opportunity/Affirmative Action Employer.

Associate Scientist I/II

MedImmune, LLC
Gaithersburg, MD

Required education: Bachelor's Degree
Area(s) of expertise desired: Clinical Research, Validation

You have a passion for excellence. At MedImmune, we do too.

MedImmune is a recognized leader in the biotechnology industry, we use the latest advances in science, technology and medicine to develop innovative products that improve the quality of human health. We strive to create a work environment that is professionally and personally rewarding, characterized by respect, integrity and opportunities for growth. Hundreds of thousands of patients have benefited from our products, which are designed to treat or prevent infectious diseases, cancer and inflammatory diseases. Our extensive research and development efforts are focused on these same areas. Both individual contributions and team successes are critical on the path to scientific and medical breakthroughs.

Position Title: Associate Scientist I/II
Department Name:
Location: Gaithersburg, MD 20878
Req Number: 00965

  • Works under general supervision to develop and validate immunoassays in support of clinical and non clinical GLP sample analyses.
  • Executes assay development, optimization, qualification and validation experiments in a GLP-compliant manner.
  • Monitors and troubleshoots assays, providing solutions for improvement using analytical tools, scientific literature, vendor information, and input from colleagues.
  • Prepares validation protocols, validation reports and summaries of assay optimizations and qualifications, updates to management.
  • Writes, updates, and reviews SOPs.
  • Presents findings at internal meetings. May present at external meetings.
  • Serves as mentor and role model to other lab personnel.
  • Candidate should have a working knowledge of the principles of ELISA immunoassays, their optimization and development. Experience in other bioanalytical methods (cell culture, FACS, Luminex, ECL) a plus.
  • GLP experience desired.
  • Good oral and written communication skills required.
  • Working knowledge of, Microsoft Word, Excel and Softmax Pro.

Requirements: Position requires a BS degree in the sciences and 5-8 years of relevant experience or a MS degree in teh sciences and 2-5 years of relevant exp. ELISA experience is a must. GLP experience is a plus.

If you are interested in this position, apply online at www.medimmune.appone.com and search for Req 00965.

MedImmune, LLC. is an Equal Opportunity Employer and does not discriminate on the basis of race, color, religion, gender, age, national origin, disability, veteran status, or any other characteristic protected by federal, state or local law.

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